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We are pleased to announce the MIDTAPICON Clinical Edge 2026 – More details

The Journal of the Association of
Physicians of Tamil Nadu

JAPTN

The Journal of the Association of
Physicians of Tamil Nadu

JAPTN

The Journal of the Association of
Physicians of Tamil Nadu

JAPTN

Home Articles Volume 4, Issue 3 A Case of Inherited Channelopathy-Liddle’s Syndrome
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A Case of Inherited Channelopathy-Liddle’s Syndrome


Volume 4, Issue 3, Pages 63-64

Authors

S. Aravind, Gunasekaran Mahalingam
Affiliation:
Consultant Physician, Green Health Hospital, Pattukkottai, Thanjavur, Tamil Nadu, India.
Senior Consultant Physician, Dravidian Speciality Hospital, Pattukkottai, Thanjavur, Tamil Nadu, India.
Corresponding Author Email[✲]:

Corresponding Author

Gunasekaran Mahalingam

Abstract

Liddle’s syndrome is a rare inherited cause of secondary hypertension, occurring due to epithelial sodium channel (ENaC) mutations. It presents either in childhood or early adulthood, as hypertension with hypokalemia, similar to mineralocorticoid excess or primary hyperaldosteronism. It can be differentiated by suppressed levels of renin and aldosterone. Treatment consists of salt restriction and ENaC blockers. Here is discussed an interesting case of Liddle’s syndrome.

Keywords

Hypertension, Hypokalemia, Liddle’s Syndrome.

Open Access

This is an open access article distributed under the CC BY 4.0 license

https://creativecommons.org/licenses/by/4.0/

Copyright

© 2026 Association of Physicians of India-Tamilnadu State Chapter. Published by Dr. Vijay Viswanathan

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Journal
Journal The Journal of the Association of Physicians of Tamil Nadu
Volume Volume 4
Issue Issue 3
Year 2025

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