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The Journal of the Association of
Physicians of Tamil Nadu

JAPTN

The Journal of the Association of
Physicians of Tamil Nadu

JAPTN

The Journal of the Association of
Physicians of Tamil Nadu

JAPTN

Home Articles Volume 2, Issue 3 Insulin Resistance in T2DM – Focus on Lobeglitazone
Research Article
Original Article

Insulin Resistance in T2DM – Focus on Lobeglitazone


Volume 2, Issue 3, Pages 1-4

Author

Dr Vijay Viswanathan
Affiliation:
Head and Chief Diabetologist, M. V. Hospital for Diabetes & Prof. M. Viswanathan Diabetes Research Centre, Chennai.

Abstract

Insulin resistance (IR) is a key underlying pathophysiology in type 2 diabetes mellitus (T2DM). Thiazolidinediones (TZDs) are oral antidiabetic drugs (OADs) that can address IR. However, their use has been limited due to the associated adverse effects. A novel TZD – Lobeglitazone – has been introduced, which is a dual agonist of peroxisome proliferator-activated receptor (PPAR) and has been reported to have a favorable safety and efficacy profile. This paper summarizes some key characteristics of this agent and the findings from two recent studies conducted in Korea and India.

Keywords

Type 2 diabetes mellitus, Lobeglitazone, insulin resistance.

Open Access

This work is licensed under the Creative Commons Attribution 4.0 International License.

https://creativecommons.org/licenses/by/4.0

Copyright

© 2023 Dr. Vijay Viswanathan, published by Association of Physicians of India-Tamilnadu State Chapter

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Journal
Journal The Journal of the Association of Physicians of Tamil Nadu
Volume Volume 2
Issue Issue 3
Year 2023

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