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We are pleased to announce the MIDTAPICON Clinical Edge 2026 – More details

The Journal of the Association of
Physicians of Tamil Nadu

JAPTN

The Journal of the Association of
Physicians of Tamil Nadu

JAPTN

The Journal of the Association of
Physicians of Tamil Nadu

JAPTN

Home › Articles › Volume 3, Issue 2 › A Common Agent: 2 Different Cases the Menace that is...
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Research Article
Original Article

A Common Agent: 2 Different Cases the Menace that is Opioid-Induced Leukoencephalopathy

Volume 3, Issue 2, Pages 8-13

Authors

Dr. Shaik Sulaiman Meeran A, Dr. S Malathi, Dr. A Revathi, Dr. Anish S Bharatwaj
Affiliation:
Professor and HOD, Department of Internal Medicine, Government Royapettah Hospital
Associate Professor, Department of Internal Medicine, Government Royapettah Hospital
Senior Assistant Professor, Department of Internal Medicine, Government Royapettah Hospital
Junior Resident, Department of Internal Medicine, Government Royapettah Hospital

Abstract

Leukoencephalopathy is a broad term used to refer to an affliction of White Matter Myelin arising from defects in either development or maintenance. There are multiple agents known to cause leukoencephalopathy, namely vascular insults, chronic inflammatory insults, infections, trauma and genetic mutations which can affect the myelin in many ways. In particular, one offending toxin with potentially lethal implications is the Opioid group of analgesics. Tapentadol is one such centrall acting Opioid Analgesic. In this article, we describe two cases of Tapentadol abuse with varied presentations and striking radiological features.

Keywords

Tapentadol, Toxic Leukoencephalopathy.

Open Access

This work is licensed under the Creative Commons Attribution 4.0 International License.

https://creativecommons.org/licenses/by/4.0

Copyright

© 2024 Dr. Vijay Viswanathan, published by Association of Physicians of India-Tamilnadu State Chapter

Cite this Article

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                                            Journal
                                            The Journal of the Association of Physicians of Tamil Nadu
                                        

                                        

                                            Volume
                                            Volume 3
                                        

                                        

                                            Issue
                                            Issue 2
                                        

                                        

                                            Year
                                            2024
                                        

                                    

                                

                            

                        

                    

                

                
                
                
                
                
                

                    

                        
                        

                            
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