Infertility, a disease affecting the reproductive system, is a widely prevalent condition. Globally, it affects millions of couples trying to conceive. A systematic evaluation of couples seeking fertility treatment is essential to provide appropriate treatment and also to help in avoiding delay in time to pregnancy.Clinically diagnosing the underlying probable cause for infertility and proper management helps these couples conceive a child. History collection plays a pivotal role in the clinical diagnosis of the cause. Since infertility is multifactorial, paramount importance should be given to eliciting a detailed history of events from childhood to date for both men and women. The scheme of the history of infertility is discussed in this article.